STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEF2DMyocyte enhancer factor 2D. (524 aa)    
Predicted Functional Partners:
MEF2A
Myocyte enhancer factor 2A.
  
 
0.968
MEF2C
Myocyte enhancer factor 2C.
  
 
0.935
MEF2B
Myocyte enhancer factor 2B.
    
0.906
HDAC4
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 
 0.883
NFATC2
Nuclear factor of activated T cells 2.
    
 0.880
NFATC1
Nuclear factor of activated T cells 1.
   
 0.869
NFATC3
Nuclear factor of activated T cells 3.
    
 0.865
MYOG
Myogenin.
    
 0.860
NFATC4
Nuclear factor of activated T cells 4.
     
 0.847
MAPK12
Mitogen-activated protein kinase.
    
 0.845
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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