STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.966
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.952
RTN4
Reticulon.
   
 0.951
Rtn3
Reticulon.
   
 0.940
RTN2
Reticulon.
   
 0.872
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
  
  
 
0.842
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 0.816
RTN1
Reticulon.
   
 0.778
APLP2
Amyloid beta precursor like protein 2.
    
 0.737
APLP1
Amyloid beta precursor like protein 1.
    
 0.727
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.