STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIK2Salt inducible kinase 2. (930 aa)    
Predicted Functional Partners:
CRTC2
CREB regulated transcription coactivator 2.
    
 0.955
CRTC3
CREB regulated transcription coactivator 3.
    
 0.915
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 
0.863
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 
0.859
CRTC1
CREB regulated transcription coactivator 1.
    
 0.801
Prkx
Uncharacterized protein.
  
 
 
0.791
PRKG1
cGMP-dependent protein kinase.
   
 
 
0.762
KSR1
Kinase suppressor of ras 1.
    
0.637
KSR2
Kinase suppressor of ras 2.
    
0.637
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
 0.615
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.