STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Il2rgFibronectin type-III domain-containing protein. (374 aa)    
Predicted Functional Partners:
IL2RB
Interleukin 2 receptor subunit beta.
  
 0.997
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
   
 0.995
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.
    
 0.995
IL4R
Interleukin 4 receptor.
    
 0.995
Il15ra
Sushi domain-containing protein.
    
 0.993
IL2RA
Interleukin 2 receptor subunit alpha.
   
 0.985
JAK3
Tyrosine-protein kinase.
   
 0.963
ALG14
ALG14 UDP-N-acetylglucosaminyltransferase subunit.
   
 0.962
IL7
Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.
   
 0.957
JAK1
Tyrosine-protein kinase.
   
 0.954
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.