spo0A protein (Clostridium kluyveri) - STRING interaction network

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spo0A

Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (271 aa)

Predicted Functional Partners:

CKL_1236

0.961

spoIIAB

0.904

CKL_1362

0.856

sigG

0.845

CKL_3720

0.834

CKL_0169

0.832

CKL_0154

0.831

sigE1

0.831

sigE2

0.827

CKL_1218

0.823

Your Current Organism:

Clostridium kluyveri

NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKL_0154	CKL_0169	CKL_0154	CKL_0169	Predicted stage V sporulation protein T.	Predicted stage II sporulation protein E.	0.814
CKL_0154	CKL_1218	CKL_0154	CKL_1218	Predicted stage V sporulation protein T.	Predicted stage III sporulation protein AA.	0.818
CKL_0154	CKL_1236	CKL_0154	CKL_1236	Predicted stage V sporulation protein T.	Predicted stage IV sporulation protein B.	0.773
CKL_0154	CKL_1362	CKL_0154	CKL_1362	Predicted stage V sporulation protein T.	Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	0.804
CKL_0154	CKL_3720	CKL_0154	CKL_3720	Predicted stage V sporulation protein T.	Predicted stage II sporulation protein R.	0.840
CKL_0154	sigE1	CKL_0154	CKL_1335	Predicted stage V sporulation protein T.	SigE1; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.756
CKL_0154	sigE2	CKL_0154	CKL_1341	Predicted stage V sporulation protein T.	SigE2; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.808
CKL_0154	sigG	CKL_0154	CKL_1342	Predicted stage V sporulation protein T.	SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.806
CKL_0154	spo0A	CKL_0154	CKL_1237	Predicted stage V sporulation protein T.	Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.831
CKL_0154	spoIIAB	CKL_0154	CKL_3155	Predicted stage V sporulation protein T.	SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.858
CKL_0169	CKL_0154	CKL_0169	CKL_0154	Predicted stage II sporulation protein E.	Predicted stage V sporulation protein T.	0.814
CKL_0169	CKL_1218	CKL_0169	CKL_1218	Predicted stage II sporulation protein E.	Predicted stage III sporulation protein AA.	0.820
CKL_0169	CKL_1236	CKL_0169	CKL_1236	Predicted stage II sporulation protein E.	Predicted stage IV sporulation protein B.	0.768
CKL_0169	CKL_1362	CKL_0169	CKL_1362	Predicted stage II sporulation protein E.	Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	0.825
CKL_0169	CKL_3720	CKL_0169	CKL_3720	Predicted stage II sporulation protein E.	Predicted stage II sporulation protein R.	0.862
CKL_0169	sigE1	CKL_0169	CKL_1335	Predicted stage II sporulation protein E.	SigE1; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.700
CKL_0169	sigE2	CKL_0169	CKL_1341	Predicted stage II sporulation protein E.	SigE2; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.736
CKL_0169	sigG	CKL_0169	CKL_1342	Predicted stage II sporulation protein E.	SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.821
CKL_0169	spo0A	CKL_0169	CKL_1237	Predicted stage II sporulation protein E.	Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.832
CKL_0169	spoIIAB	CKL_0169	CKL_3155	Predicted stage II sporulation protein E.	SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.879

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