STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKL_3682Stage III sporulation protein D. (84 aa)    
Predicted Functional Partners:
CKL_1222
Predicted stage III sporulation protein AE.
  
    0.924
CKL_1362
Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.869
CKL_0154
Predicted stage V sporulation protein T.
  
  
 0.856
CKL_3720
Predicted stage II sporulation protein R.
  
   
 0.848
CKL_1218
Predicted stage III sporulation protein AA.
  
   
 0.842
spoIIAB
SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.839
CKL_0896
Predicted stage II sporulation protein P.
  
  
 0.831
spo0A
Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.830
CKL_0169
Predicted stage II sporulation protein E.
  
   
 0.827
CKL_1220
Predicted stage III sporulation protein AC.
  
  
 0.827
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
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