node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKL_3902 | dnaE | CKL_3902 | CKL_3560 | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DnaE; DNA polymerase III, alpha subunit. | 0.424 |
CKL_3902 | rplI | CKL_3902 | CKL_3904 | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | RplI; Binds to the 23S rRNA. | 0.701 |
CKL_3902 | rpsR | CKL_3902 | CKL_3908 | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | RpsR; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.498 |
CKL_3902 | ssb3 | CKL_3902 | CKL_3909 | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Ssb3; Predicted single-strand binding protein. | 0.786 |
CKL_3902 | topA | CKL_3902 | CKL_1415 | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.499 |
CKL_3902 | topA2 | CKL_3902 | CKL_1068 | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | TopA2; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finall [...] | 0.432 |
CKL_3911 | rplI | CKL_3911 | CKL_3904 | Conserved hypothetical protein. | RplI; Binds to the 23S rRNA. | 0.550 |
CKL_3911 | rpsF | CKL_3911 | CKL_3910 | Conserved hypothetical protein. | RpsF; Binds together with S18 to 16S ribosomal RNA. | 0.676 |
CKL_3911 | rpsR | CKL_3911 | CKL_3908 | Conserved hypothetical protein. | RpsR; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.649 |
CKL_3911 | ssb1 | CKL_3911 | CKL_1147 | Conserved hypothetical protein. | Ssb1; Single-stranded DNA-binding protein. | 0.598 |
CKL_3911 | ssb3 | CKL_3911 | CKL_3909 | Conserved hypothetical protein. | Ssb3; Predicted single-strand binding protein. | 0.714 |
dnaE | CKL_3902 | CKL_3560 | CKL_3902 | DnaE; DNA polymerase III, alpha subunit. | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.424 |
dnaE | ssb1 | CKL_3560 | CKL_1147 | DnaE; DNA polymerase III, alpha subunit. | Ssb1; Single-stranded DNA-binding protein. | 0.709 |
dnaE | ssb3 | CKL_3560 | CKL_3909 | DnaE; DNA polymerase III, alpha subunit. | Ssb3; Predicted single-strand binding protein. | 0.753 |
dnaE | topA | CKL_3560 | CKL_1415 | DnaE; DNA polymerase III, alpha subunit. | Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.533 |
dnaE | topA2 | CKL_3560 | CKL_1068 | DnaE; DNA polymerase III, alpha subunit. | TopA2; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finall [...] | 0.533 |
rplI | CKL_3902 | CKL_3904 | CKL_3902 | RplI; Binds to the 23S rRNA. | Predicted DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.701 |
rplI | CKL_3911 | CKL_3904 | CKL_3911 | RplI; Binds to the 23S rRNA. | Conserved hypothetical protein. | 0.550 |
rplI | rplJ | CKL_3904 | CKL_0214 | RplI; Binds to the 23S rRNA. | RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.984 |
rplI | rpsF | CKL_3904 | CKL_3910 | RplI; Binds to the 23S rRNA. | RpsF; Binds together with S18 to 16S ribosomal RNA. | 0.994 |