node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMR66009.1 | AMR66012.1 | A0T30_06370 | A0T30_06385 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.601 |
AMR66009.1 | ureA | A0T30_06370 | A0T30_06375 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.892 |
AMR66009.1 | ureB | A0T30_06370 | A0T30_06365 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.836 |
AMR66009.1 | ureC | A0T30_06370 | A0T30_06360 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.693 |
AMR66009.1 | ureD | A0T30_06370 | A0T30_06380 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.879 |
AMR66012.1 | AMR66009.1 | A0T30_06385 | A0T30_06370 | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.601 |
AMR66012.1 | ureA | A0T30_06385 | A0T30_06375 | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.605 |
AMR66012.1 | ureB | A0T30_06385 | A0T30_06365 | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.601 |
AMR66012.1 | ureC | A0T30_06385 | A0T30_06360 | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.438 |
AMR66012.1 | ureD | A0T30_06385 | A0T30_06380 | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.605 |
AMR68281.1 | gltB | A0T30_18575 | A0T30_04405 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
AMR68281.1 | ureD | A0T30_18575 | A0T30_06380 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.563 |
gltB | AMR68281.1 | A0T30_04405 | A0T30_18575 | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
gltB | ureA | A0T30_04405 | A0T30_06375 | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.435 |
gltB | ureB | A0T30_04405 | A0T30_06365 | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.426 |
gltB | ureC | A0T30_04405 | A0T30_06360 | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.433 |
gltB | ureD | A0T30_04405 | A0T30_06380 | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.497 |
gltB | ureG | A0T30_04405 | A0T30_18475 | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.400 |
ureA | AMR66009.1 | A0T30_06375 | A0T30_06370 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
ureA | AMR66012.1 | A0T30_06375 | A0T30_06385 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.605 |