STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rraARibonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (162 aa)    
Predicted Functional Partners:
AMR67112.1
CmaX protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.774
AMR67110.1
Rieske iron-sulfur protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.734
AMR67114.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.648
AMR67109.1
EstX protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.641
AMR67113.1
CrfX protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.624
sigX
RNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in Pseudomonas fluorescens and P. aeruginosa regulates outer membrane protein OprF expression; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.497
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.474
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
     0.454
AMR67106.1
3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.443
AMR68435.1
Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.420
Your Current Organism:
Pseudomonas alcaligenes
NCBI taxonomy Id: 43263
Other names: ATCC 14909, CFBP 2437, CIP 101034, DSM 50342, IAM 12411, IFO 14159, JCM 5967, NBRC 14159, NCCB 76044, NCTC 10367, P. alcaligenes, VKM B-2171
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