STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMR68424.1DNA topoisomerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)    
Predicted Functional Partners:
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
  
    0.842
AMR68425.1
Aspartyl protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.825
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
  
    0.824
AMR68422.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.770
AMR68430.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.684
AMR68427.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.674
AMR68428.1
Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.674
AMR68429.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.674
cpdA
Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.624
AMR68431.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.500
Your Current Organism:
Pseudomonas alcaligenes
NCBI taxonomy Id: 43263
Other names: ATCC 14909, CFBP 2437, CIP 101034, DSM 50342, IAM 12411, IFO 14159, JCM 5967, NBRC 14159, NCCB 76044, NCTC 10367, P. alcaligenes, VKM B-2171
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