STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMR68438.1TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (628 aa)    
Predicted Functional Partners:
AMR67835.1
Protein TolA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.697
AMR65029.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 
 0.692
AMR68228.1
Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
   
 
 0.651
AMR65490.1
Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.619
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.607
tolB
Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
    
 
 0.542
AMR68701.1
precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.517
lptE
Hypothetical protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
  
  
 0.489
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.483
AMR68409.1
Channel protein TolC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.457
Your Current Organism:
Pseudomonas alcaligenes
NCBI taxonomy Id: 43263
Other names: ATCC 14909, CFBP 2437, CIP 101034, DSM 50342, IAM 12411, IFO 14159, JCM 5967, NBRC 14159, NCCB 76044, NCTC 10367, P. alcaligenes, VKM B-2171
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.