IF1G_09406 protein (Cordyceps javanica) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

IF1G_09406

Chaperone protein dnaJ 2. (427 aa)

Predicted Functional Partners:

IF1G_10352

0.967

IF1G_07219

0.940

IF1G_00497

0.937

IF1G_02645

0.937

IF1G_07848

0.936

IF1G_04609

0.907

IF1G_10216

0.891

IF1G_04672

0.891

IF1G_04884

0.889

IF1G_05162

0.888

Your Current Organism:

Cordyceps javanica

NCBI taxonomy Id: 43265
Other names: C. javanica, CBS 134.22, Cordyceps javanica (Frieder. & Bally) Kepler, B. Shrestha & Spatafora, 2017, Isaria javanica, Isaria javanicus, Paecilomyces javanica, Paecilomyces sp. ARSEF 3776, Paecilomyces sp. ARSEF 3778, Spicaria javanica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IF1G_00497	IF1G_02645	A0A545VFR8	A0A545W711	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	0.933
IF1G_00497	IF1G_04609	A0A545VFR8	A0A545V6L5	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Mitochondrial protein import protein MAS5.	0.943
IF1G_00497	IF1G_04672	A0A545VFR8	A0A545W083	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Hamartin.	0.934
IF1G_00497	IF1G_04884	A0A545VFR8	A0A545V3L3	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock protein.	0.961
IF1G_00497	IF1G_05162	A0A545VFR8	A0A545V4E0	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock protein Hsp88.	0.918
IF1G_00497	IF1G_07219	A0A545VFR8	A0A545VWY6	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	ER associated DnaJ chaperone (Hlj1).	0.749
IF1G_00497	IF1G_09406	A0A545VFR8	A0A545UQS7	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Chaperone protein dnaJ 2.	0.937
IF1G_00497	IF1G_10216	A0A545VFR8	A0A545VLW9	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock protein 82.	0.954
IF1G_00497	IF1G_10352	A0A545VFR8	A0A545VMD3	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	DnaJ domain-containing protein.	0.974
IF1G_02645	IF1G_00497	A0A545W711	A0A545VFR8	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	0.933
IF1G_02645	IF1G_04609	A0A545W711	A0A545V6L5	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Mitochondrial protein import protein MAS5.	0.948
IF1G_02645	IF1G_04672	A0A545W711	A0A545W083	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Hamartin.	0.937
IF1G_02645	IF1G_04884	A0A545W711	A0A545V3L3	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock protein.	0.961
IF1G_02645	IF1G_05162	A0A545W711	A0A545V4E0	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock protein Hsp88.	0.918
IF1G_02645	IF1G_07219	A0A545W711	A0A545VWY6	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	ER associated DnaJ chaperone (Hlj1).	0.763
IF1G_02645	IF1G_07848	A0A545W711	A0A545VUG8	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Regulator protein; Belongs to the heat shock protein 70 family.	0.806
IF1G_02645	IF1G_09406	A0A545W711	A0A545UQS7	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Chaperone protein dnaJ 2.	0.937
IF1G_02645	IF1G_10216	A0A545W711	A0A545VLW9	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Heat shock protein 82.	0.950
IF1G_02645	IF1G_10352	A0A545W711	A0A545VMD3	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	DnaJ domain-containing protein.	0.975
IF1G_04609	IF1G_00497	A0A545V6L5	A0A545VFR8	Mitochondrial protein import protein MAS5.	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	0.943

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Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.879

expected number of edges:

12

PPI enrichment p-value:

3.28e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022900

Electron transport chain

5 of 17

1.81

2.24

9.42e-06

GO:0006119

Oxidative phosphorylation

3 of 7

1.97

1.53

0.00092

GO:0009060

Aerobic respiration

4 of 20

1.64

1.49

0.00046

GO:0042773

ATP synthesis coupled electron transport

2 of 5

1.94

0.8

0.0311

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015078

Proton transmembrane transporter activity

5 of 14

1.89

2.44

4.55e-06

GO:0016682

Oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor

3 of 3

2.34

1.95

0.00021

GO:0004129

Cytochrome-c oxidase activity

3 of 4

2.22

1.88

0.00024

GO:0009055

Electron transfer activity

4 of 13

1.83

1.79

0.00016

GO:0005507

Copper ion binding

2 of 7

1.8

0.81

0.0269

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070469

Respirasome

2 of 2

2.34

1.32

0.0035

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

2 of 3

2.17

1.25

0.0044

GO:0005886

Plasma membrane

9 of 396

0.7

0.59

0.00035

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2151

Cytochrome-c oxidase activity, and Heme biosynthesis

5 of 7

2.2

3.21

2.90e-07

CL:1031

CoA-ligase, and Alpha-helical ferredoxin

2 of 5

1.94

0.82

0.0273

CL:2023

Mixed, incl. Peptidase M16, C-terminal, and Phosphatidylglycerol metabolic process

2 of 7

1.8

0.72

0.0414

CL:263

ATP synthesis

2 of 8

1.74

0.69

0.0464

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

shh00190

Oxidative phosphorylation

9 of 23

1.93

5.03

1.87e-14

shh01100

Metabolic pathways

9 of 477

0.62

0.5

0.00089

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070469

Respirasome

3 of 9

1.86

1.36

0.0018

GOCC:0009319

Cytochrome o ubiquinol oxidase complex

2 of 2

2.34

1.18

0.0066

GOCC:0098796

Membrane protein complex

5 of 60

1.26

1.08

0.0011

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

2 of 4

2.04

1.03

0.0110

GOCC:0016020

Membrane

8 of 402

0.64

0.47

0.0050

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0679

Respiratory chain

2 of 2

2.34

0.91

0.0217

KW-0138

CF(0)

2 of 3

2.17

0.9

0.0217

KW-0066

ATP synthesis

2 of 8

1.74

0.72

0.0401

KW-0813

Transport

4 of 121

0.86

0.47

0.0438

KW-1133

Transmembrane helix

7 of 452

0.53

0.33

0.0438

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF05193

Peptidase M16 inactive domain

2 of 2

2.34

0.75

0.0429

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