STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IF1G_00145CS domain-containing protein. (188 aa)    
Predicted Functional Partners:
IF1G_05735
Serine/threonine-protein kinase plo1.
    
 0.987
PAC1
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.
    
 0.932
IF1G_09027
Nuclear distribution protein nudE.
     
 0.858
IF1G_04887
Dynamin gtpase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.839
IF1G_05828
Checkpoint protein kinase (SldA).
     
 0.794
IF1G_02688
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
     
 0.794
IF1G_03720
Dynein light intermediate chain.
    
 0.786
IF1G_08619
Spindle assembly checkpoint component MAD1.
    
  0.770
IF1G_04607
Noc1p protein.
     
 0.757
IF1G_06939
Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
     
 0.756
Your Current Organism:
Cordyceps javanica
NCBI taxonomy Id: 43265
Other names: C. javanica, CBS 134.22, Cordyceps javanica (Frieder. & Bally) Kepler, B. Shrestha & Spatafora, 2017, Isaria javanica, Isaria javanicus, Paecilomyces javanica, Paecilomyces sp. ARSEF 3776, Paecilomyces sp. ARSEF 3778, Spicaria javanica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.