node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IF1G_00830 | IF1G_02121 | A0A545VGN3 | A0A545VDV3 | DNA mismatch repair protein Msh4. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.836 |
IF1G_00830 | IF1G_04015 | A0A545VGN3 | A0A545W244 | DNA mismatch repair protein Msh4. | EXO1 protein. | 0.839 |
IF1G_00830 | IF1G_04034 | A0A545VGN3 | A0A545V507 | DNA mismatch repair protein Msh4. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.878 |
IF1G_00830 | IF1G_04712 | A0A545VGN3 | A0A545V333 | DNA mismatch repair protein Msh4. | DNA mismatch repair protein Mlh1. | 0.944 |
IF1G_00830 | IF1G_04767 | A0A545VGN3 | A0A545V396 | DNA mismatch repair protein Msh4. | Acetamidase/formamidase. | 0.881 |
IF1G_00830 | IF1G_05209 | A0A545VGN3 | A0A545W1P0 | DNA mismatch repair protein Msh4. | DNA mismatch repair protein (Pms1). | 0.934 |
IF1G_00830 | IF1G_05596 | A0A545VGN3 | A0A545VZ86 | DNA mismatch repair protein Msh4. | DNA mismatch repair protein. | 0.953 |
IF1G_00830 | IF1G_05852 | A0A545VGN3 | A0A545V2U5 | DNA mismatch repair protein Msh4. | MutS domain V. | 0.997 |
IF1G_00830 | IF1G_06086 | A0A545VGN3 | A0A545VVI6 | DNA mismatch repair protein Msh4. | AAA-ATPase vps4-associated protein 1 domain-containing protein. | 0.917 |
IF1G_00830 | IF1G_10969 | A0A545VGN3 | A0A545VJI6 | DNA mismatch repair protein Msh4. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.778 |
IF1G_02121 | IF1G_00830 | A0A545VDV3 | A0A545VGN3 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA mismatch repair protein Msh4. | 0.836 |
IF1G_02121 | IF1G_04015 | A0A545VDV3 | A0A545W244 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | EXO1 protein. | 0.842 |
IF1G_02121 | IF1G_04034 | A0A545VDV3 | A0A545V507 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.788 |
IF1G_02121 | IF1G_04712 | A0A545VDV3 | A0A545V333 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA mismatch repair protein Mlh1. | 0.622 |
IF1G_02121 | IF1G_05852 | A0A545VDV3 | A0A545V2U5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | MutS domain V. | 0.804 |
IF1G_02121 | IF1G_06086 | A0A545VDV3 | A0A545VVI6 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | AAA-ATPase vps4-associated protein 1 domain-containing protein. | 0.420 |
IF1G_02121 | IF1G_10969 | A0A545VDV3 | A0A545VJI6 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.985 |
IF1G_04015 | IF1G_00830 | A0A545W244 | A0A545VGN3 | EXO1 protein. | DNA mismatch repair protein Msh4. | 0.839 |
IF1G_04015 | IF1G_02121 | A0A545W244 | A0A545VDV3 | EXO1 protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.842 |
IF1G_04015 | IF1G_04034 | A0A545W244 | A0A545V507 | EXO1 protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.978 |