STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topAUnannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (950 aa)    
Predicted Functional Partners:
A5792_10035
Unannotated protein.
  
 0.999
A5792_31385
Unannotated protein.
  
 0.988
A5792_28580
Unannotated protein.
    
 0.986
polA
Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.977
recA
Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
 0.971
GCA_001403655_00588
Unannotated protein.
  
 0.936
A5792_19305
Unannotated protein.
  
 0.914
leuS
Unannotated protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 
 0.912
A5792_08825
Unannotated protein.
  
 0.860
A5792_26445
Unannotated protein.
 
 0.858
Your Current Organism:
Mycolicibacterium peregrinum
NCBI taxonomy Id: 43304
Other names: ATCC 14467, CCUG 27976, CIP 105382, DSM 43271, JCM 12142, M. peregrinum, Mycobacterium fortuitum biovar peregrinum, Mycobacterium peregrinum, NCTC 10264
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.