node1 | node2 | node1 annotation | node2 annotation | score |
A0A4U5NKM5 | A0A4U5NNG6 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Core region of GTP cyclohydrolase I family protein. | 0.999 |
A0A4U5NKM5 | A0A4U5PT57 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Mur_ligase_M domain-containing protein. | 0.955 |
A0A4U5NKM5 | A0A4U5Q347 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Pterin-binding domain-containing protein. | 0.999 |
A0A4U5NKM5 | A0A4U5Q462 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional dihydrofolate reductase-thymidylate synthase-like; Belongs to the dihydrofolate reductase family. | 0.654 |
A0A4U5NKM5 | A0A4U5QAL8 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.654 |
A0A4U5NKM5 | A0A4U5QMC2 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Folylpolyglutamate synthase-like isoform X1. | 0.955 |
A0A4U5NKM5 | A0A4U5QNX0 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Core region of GTP cyclohydrolase I family protein. | 0.999 |
A0A4U5NKM5 | A0A4U5R3N8 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.955 |
A0A4U5NKM5 | A0A4U5R548 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative dihydrofolate synthetase isoform X1. | 0.956 |
A0A4U5NKM5 | A0A4V6A413 | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.654 |
A0A4U5NNG6 | A0A4U5NKM5 | Core region of GTP cyclohydrolase I family protein. | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
A0A4U5NNG6 | A0A4U5PT57 | Core region of GTP cyclohydrolase I family protein. | Mur_ligase_M domain-containing protein. | 0.639 |
A0A4U5NNG6 | A0A4U5Q347 | Core region of GTP cyclohydrolase I family protein. | Pterin-binding domain-containing protein. | 0.999 |
A0A4U5NNG6 | A0A4U5Q462 | Core region of GTP cyclohydrolase I family protein. | Bifunctional dihydrofolate reductase-thymidylate synthase-like; Belongs to the dihydrofolate reductase family. | 0.616 |
A0A4U5NNG6 | A0A4U5QAL8 | Core region of GTP cyclohydrolase I family protein. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.616 |
A0A4U5NNG6 | A0A4U5QMC2 | Core region of GTP cyclohydrolase I family protein. | Folylpolyglutamate synthase-like isoform X1. | 0.639 |
A0A4U5NNG6 | A0A4U5R3N8 | Core region of GTP cyclohydrolase I family protein. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.639 |
A0A4U5NNG6 | A0A4U5R548 | Core region of GTP cyclohydrolase I family protein. | Putative dihydrofolate synthetase isoform X1. | 0.707 |
A0A4U5NNG6 | A0A4V6A413 | Core region of GTP cyclohydrolase I family protein. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.616 |
A0A4U5PT57 | A0A4U5NKM5 | Mur_ligase_M domain-containing protein. | 7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.955 |