STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCF7L2Transcription factor 7 like 2. (536 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.997
JUP
Junction plakoglobin.
    
 0.962
NLK
Nemo like kinase.
    
 0.962
AXIN2
Axin 2.
   
 0.920
EP300
E1A binding protein p300.
   
 0.918
CREBBP
CREB binding protein.
   
 0.917
SMAD4
SMAD family member 4.
    
 0.914
ENSBBBP00000018413
annotation not available
    
 0.913
APC2
APC regulator of WNT signaling pathway 2.
    
 0.904
TCF7L1
Transcription factor 7 like 1.
     
0.904
Your Current Organism:
Bison bison
NCBI taxonomy Id: 43346
Other names: B. bison bison, Bison bison bison, Bos bison bison
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.