STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERN1Endoplasmic reticulum to nucleus signaling 1. (974 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5.
    
 0.994
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
   
0.977
TRAF2
TNF receptor associated factor 2.
   
 0.971
PSEN1
Presenilin 1.
    
 0.951
PSEN2
Presenilin 2.
    
 0.948
XBP1
X-box binding protein 1.
    
 0.902
ENSBBBP00000006303
annotation not available
    
 0.775
FAS
Fas cell surface death receptor.
   
 0.764
TRAF1
TNF receptor associated factor 1.
   
 0.686
SYVN1
Synoviolin 1.
    
 
 0.641
Your Current Organism:
Bison bison
NCBI taxonomy Id: 43346
Other names: B. bison bison, Bison bison bison, Bos bison bison
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.