STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT4Sirtuin 4. (315 aa)    
Predicted Functional Partners:
NAMPT
Nicotinamide phosphoribosyltransferase.
     
 0.963
NADK
NAD kinase.
  
 
 0.955
NUDT12
Nudix hydrolase 12.
    
 0.950
NNT
Nicotinamide nucleotide transhydrogenase.
   
 
 0.944
NADSYN1
NAD synthetase 1.
    
 0.914
NMNAT1
Nicotinamide nucleotide adenylyltransferase 1.
    
 0.908
SIRT3
Sirtuin 3.
  
 
0.904
ENSBBBP00000001119
annotation not available
   
 0.901
ENSBBBP00000006036
annotation not available
     
 0.898
SIRT5
Sirtuin 5.
  
 
0.895
Your Current Organism:
Bison bison
NCBI taxonomy Id: 43346
Other names: B. bison bison, Bison bison bison, Bos bison bison
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.