STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AURKAAurora kinase A. (402 aa)    
Predicted Functional Partners:
TPX2
TPX2 microtubule nucleation factor.
   
 0.985
ENSBBBP00000010759
annotation not available
   
 0.984
TP53
Tumor protein p53.
   
 0.978
INCENP
Inner centromere protein.
   
 0.972
CDC20
Cell division cycle 20.
   
 0.967
PLK1
Polo like kinase 1.
   
0.966
ENSBBBP00000015251
annotation not available
   
 0.955
ENSBBBP00000019265
annotation not available
   
 0.954
ENSBBBP00000006164
annotation not available
   
 0.947
CDCA8
Cell division cycle associated 8.
   
 0.947
Your Current Organism:
Bison bison
NCBI taxonomy Id: 43346
Other names: B. bison bison, Bison bison bison, Bos bison bison
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.