Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORA33009.1TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)    
Predicted Functional Partners:
ORA32983.1
enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.914
ORA32981.1
L-asparagine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.733
ORA32982.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.688
ORA32219.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.592
ORA39480.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.495
ORA36694.1
Acetoacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.459
ORA37929.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.458
ORA32009.1
Mammalian cell entry protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.439
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
   
   0.419
ORA32005.1
Mammalian cell entry protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.414
Your Current Organism:
Mycobacterium branderi
NCBI taxonomy Id: 43348
Other names: ATCC 51789, CIP 104592, DSM 44624, JCM 12687, M. branderi, strain 52157
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