node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NRI_0790 | NRI_0847 | NRI_0790 | NRI_0847 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | Putative N utilization substance protein B. | 0.698 |
NRI_0790 | NRI_0854 | NRI_0790 | NRI_0854 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | 0.688 |
NRI_0790 | def | NRI_0790 | NRI_0373 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.530 |
NRI_0790 | fmt | NRI_0790 | NRI_0090 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.979 |
NRI_0790 | glyA | NRI_0790 | NRI_0210 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.985 |
NRI_0790 | pheT | NRI_0790 | NRI_0403 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.506 |
NRI_0790 | purN | NRI_0790 | NRI_0449 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.969 |
NRI_0790 | thyX | NRI_0790 | NRI_0159 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.913 |
NRI_0847 | NRI_0790 | NRI_0847 | NRI_0790 | Putative N utilization substance protein B. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | 0.698 |
NRI_0847 | fmt | NRI_0847 | NRI_0090 | Putative N utilization substance protein B. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.848 |
NRI_0847 | pheT | NRI_0847 | NRI_0403 | Putative N utilization substance protein B. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.673 |
NRI_0854 | NRI_0790 | NRI_0854 | NRI_0790 | GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | 0.688 |
NRI_0854 | fmt | NRI_0854 | NRI_0090 | GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.643 |
NRI_0854 | glyA | NRI_0854 | NRI_0210 | GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.700 |
NRI_0854 | metG | NRI_0854 | NRI_0860 | GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.727 |
NRI_0854 | pheT | NRI_0854 | NRI_0403 | GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.936 |
NRI_0854 | purN | NRI_0854 | NRI_0449 | GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.669 |
def | NRI_0790 | NRI_0373 | NRI_0790 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | 0.530 |
def | fmt | NRI_0373 | NRI_0090 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.933 |
fmt | NRI_0790 | NRI_0090 | NRI_0790 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Identified by match to protein family HMM PF02882. | 0.979 |