| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NRI_0289 | NRI_0785 | NRI_0289 | NRI_0785 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | DnaJ domain protein; Identified by match to protein family HMM PF00226. | 0.931 |
| NRI_0289 | dnaJ | NRI_0289 | NRI_0512 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.990 |
| NRI_0289 | groL | NRI_0289 | NRI_0614 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.958 |
| NRI_0289 | groS | NRI_0289 | NRI_0615 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.920 |
| NRI_0289 | grpE | NRI_0289 | NRI_0204 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.968 |
| NRI_0289 | hslU | NRI_0289 | NRI_0172 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | 0.665 |
| NRI_0289 | hslV | NRI_0289 | NRI_0171 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.585 |
| NRI_0289 | htpG | NRI_0289 | NRI_0467 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | Chaperone protein HtpG (Heat shock protein htpG) (High temperatureprotein G); Molecular chaperone. Has ATPase activity. | 0.978 |
| NRI_0289 | lon | NRI_0289 | NRI_0338 | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.783 |
| NRI_0785 | NRI_0289 | NRI_0785 | NRI_0289 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | 0.931 |
| NRI_0785 | dnaK | NRI_0785 | NRI_0017 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.931 |
| NRI_0785 | groL | NRI_0785 | NRI_0614 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.878 |
| NRI_0785 | groS | NRI_0785 | NRI_0615 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.680 |
| NRI_0785 | grpE | NRI_0785 | NRI_0204 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.919 |
| NRI_0785 | hslU | NRI_0785 | NRI_0172 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | 0.730 |
| NRI_0785 | hslV | NRI_0785 | NRI_0171 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.585 |
| NRI_0785 | htpG | NRI_0785 | NRI_0467 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperone protein HtpG (Heat shock protein htpG) (High temperatureprotein G); Molecular chaperone. Has ATPase activity. | 0.954 |
| NRI_0785 | lon | NRI_0785 | NRI_0338 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.710 |
| dnaJ | NRI_0289 | NRI_0512 | NRI_0289 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | 0.990 |
| dnaJ | dnaK | NRI_0512 | NRI_0017 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.996 |
