pleC-2 protein (Neorickettsia risticii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pleC-2

Sensor histidine kinase, PleC-like protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518. (519 aa)

Predicted Functional Partners:

ctrA

0.908

pleD

0.897

cckA

0.743

pdhB

0.659

cycM

0.655

NRI_0782

0.641

recA

0.639

NRI_0651

0.538

clpP

0.537

gap

0.526

Your Current Organism:

Neorickettsia risticii

NCBI taxonomy Id: 434131
Other names: N. risticii str. Illinois, Neorickettsia risticii str. Illinois, Neorickettsia risticii strain Illinois

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NRI_0651	NRI_0782	NRI_0651	NRI_0782	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	0.526
NRI_0651	cckA	NRI_0651	NRI_0351	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	0.619
NRI_0651	clpP	NRI_0651	NRI_0725	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.800
NRI_0651	gap	NRI_0651	NRI_0410	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.673
NRI_0651	pleC-2	NRI_0651	NRI_0508	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	Sensor histidine kinase, PleC-like protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.	0.538
NRI_0651	pleD	NRI_0651	NRI_0485	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	Response regulator/GGDEF domain protein PleD; Identified by match to protein family HMM PF00072; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	0.424
NRI_0651	recA	NRI_0651	NRI_0507	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.978
NRI_0782	NRI_0651	NRI_0782	NRI_0651	Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	0.526
NRI_0782	cckA	NRI_0782	NRI_0351	Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	0.641
NRI_0782	clpP	NRI_0782	NRI_0725	Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.660
NRI_0782	pdhB	NRI_0782	NRI_0720	Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.966
NRI_0782	pleC-2	NRI_0782	NRI_0508	Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	Sensor histidine kinase, PleC-like protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.	0.641
cckA	NRI_0651	NRI_0351	NRI_0651	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	0.619
cckA	NRI_0782	NRI_0351	NRI_0782	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.	0.641
cckA	clpP	NRI_0351	NRI_0725	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.815
cckA	ctrA	NRI_0351	NRI_0226	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	DNA-binding response regulator CtrA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.	0.960
cckA	cycM	NRI_0351	NRI_0448	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Identified by match to protein family HMM PF00034.	0.775
cckA	gap	NRI_0351	NRI_0410	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.747
cckA	pdhB	NRI_0351	NRI_0720	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.659
cckA	pleC-2	NRI_0351	NRI_0508	Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Sensor histidine kinase, PleC-like protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.	0.743

page 1 of 4

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2026

Credits

Access

Info

About