NRI_0616 protein (Neorickettsia risticii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

NRI_0616

Conserved hypothetical protein. (314 aa)

Predicted Functional Partners:

NRI_0163

0.917

dnaX

0.916

dnaN

0.909

NRI_0361

0.909

NRI_0617

0.791

NRI_0651

0.649

dnaQ

0.619

pcnB

0.602

groL

0.562

groS

0.557

Your Current Organism:

Neorickettsia risticii

NCBI taxonomy Id: 434131
Other names: N. risticii str. Illinois, Neorickettsia risticii str. Illinois, Neorickettsia risticii strain Illinois

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NRI_0163	NRI_0361	NRI_0163	NRI_0361	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	Conserved hypothetical protein.	0.988
NRI_0163	NRI_0616	NRI_0163	NRI_0616	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	Conserved hypothetical protein.	0.917
NRI_0163	NRI_0651	NRI_0163	NRI_0651	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	0.687
NRI_0163	dnaN	NRI_0163	NRI_0166	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.990
NRI_0163	dnaQ	NRI_0163	NRI_0445	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.991
NRI_0163	dnaX	NRI_0163	NRI_0465	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.991
NRI_0361	NRI_0163	NRI_0361	NRI_0163	Conserved hypothetical protein.	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	0.988
NRI_0361	NRI_0616	NRI_0361	NRI_0616	Conserved hypothetical protein.	Conserved hypothetical protein.	0.909
NRI_0361	NRI_0651	NRI_0361	NRI_0651	Conserved hypothetical protein.	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	0.921
NRI_0361	dnaN	NRI_0361	NRI_0166	Conserved hypothetical protein.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.997
NRI_0361	dnaQ	NRI_0361	NRI_0445	Conserved hypothetical protein.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.946
NRI_0361	dnaX	NRI_0361	NRI_0465	Conserved hypothetical protein.	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.991
NRI_0616	NRI_0163	NRI_0616	NRI_0163	Conserved hypothetical protein.	DNA polymerase III subunit alpha; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	0.917
NRI_0616	NRI_0361	NRI_0616	NRI_0361	Conserved hypothetical protein.	Conserved hypothetical protein.	0.909
NRI_0616	NRI_0617	NRI_0616	NRI_0617	Conserved hypothetical protein.	Rotamase family protein; Matched to COG0760: Parvulin-like peptidyl-prolyl isomerase; Completely overlapped with NRI_0618.	0.791
NRI_0616	NRI_0651	NRI_0616	NRI_0651	Conserved hypothetical protein.	DNA polymerase I; Identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.	0.649
NRI_0616	dnaN	NRI_0616	NRI_0166	Conserved hypothetical protein.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.909
NRI_0616	dnaQ	NRI_0616	NRI_0445	Conserved hypothetical protein.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.619
NRI_0616	dnaX	NRI_0616	NRI_0465	Conserved hypothetical protein.	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.916
NRI_0616	groL	NRI_0616	NRI_0614	Conserved hypothetical protein.	Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.562