STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRI_0670biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM TIGR00121. (226 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.953
NRI_0781
propionyl-CoA carboxylase alpha chain; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; match to protein family HMM PF08443.
 
  
 0.953
NRI_0763
propionyl-CoA carboxylase beta chain; Identified by match to protein family HMM PF01039.
  
 
 0.944
NRI_0668
NADH-quinone oxidoreductase chain m; Identified by match to protein family HMM PF00361; match to protein family HMM TIGR01972.
  
  
 0.701
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.651
NRI_0854
GMP synthase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888.
     
 0.613
NRI_0399
NADP-dependent malic enzyme, N-terminal fragment; Contains a authentic frameshift if combined with NRI_0400 (ORF00385) according to frameshift analysis. Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.
     
 0.605
NRI_0400
NADP-dependent malic enzyme, C-terminal fragment; Contains a frameshift based on matches to NSE_0420, if combined with NRI_0399 (ORF00384).
     
 0.605
cckA
Sensor histidine kinase/response regulator CckA; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
 
  
 0.586
nuoN
NADH dehydrogenase i, n subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
  
    0.564
Your Current Organism:
Neorickettsia risticii
NCBI taxonomy Id: 434131
Other names: N. risticii str. Illinois, Neorickettsia risticii str. Illinois, Neorickettsia risticii strain Illinois
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