STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRI_0927Phage uncharacterized protein; Identified by match to protein family HMM PF03237; match to protein family HMM TIGR01630. (465 aa)    
Predicted Functional Partners:
NRI_0481
Identified by match to protein family HMM PF01381; match to protein family HMM PF07022.
 
     0.617
NRI_0926
Conserved hypothetical protein.
       0.553
NRI_0620
Conserved hypothetical protein.
     
 0.487
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.476
NRI_0830
Type IV secretion system protein VirB6; Identified by match to protein family HMM PF04610.
  
     0.466
NRI_0005
Identified by match to protein family HMM PF01547.
      
 0.465
NRI_0829
Type IV secretion system protein, VirB6 family; Identified by match to protein family HMM PF04610.
  
     0.442
NRI_0007
Phage portal protein, HK97 family; Identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537.
 
    0.434
NRI_0519
RDD family protein; Identified by match to protein family HMM PF06271.
  
     0.418
NRI_0832
Type IV secretion system protein VirB3; Identified by match to protein family HMM PF05101.
  
     0.418
Your Current Organism:
Neorickettsia risticii
NCBI taxonomy Id: 434131
Other names: N. risticii str. Illinois, Neorickettsia risticii str. Illinois, Neorickettsia risticii strain Illinois
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.