node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQS84164.1 | AQS84165.1 | A0U92_04570 | A0U92_04575 | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.443 |
AQS84165.1 | AQS84164.1 | A0U92_04575 | A0U92_04570 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.443 |
AQS84165.1 | AQS84167.1 | A0U92_04575 | A0U92_04585 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.868 |
AQS84165.1 | AQS84168.1 | A0U92_04575 | A0U92_04590 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.876 |
AQS84165.1 | glyA | A0U92_04575 | A0U92_04580 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.655 |
AQS84165.1 | ilvD | A0U92_04575 | A0U92_00345 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.499 |
AQS84165.1 | leuC | A0U92_04575 | A0U92_01840 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.499 |
AQS84165.1 | leuD | A0U92_04575 | A0U92_01835 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.499 |
AQS84165.1 | lldD | A0U92_04575 | A0U92_07910 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha-hydroxy-acid oxidizing enzyme; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.618 |
AQS84165.1 | rlmJ | A0U92_04575 | A0U92_05585 | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lactate dehydrogenase; Specifically methylates the adenine in position 2030 of 23S rRNA. | 0.437 |
AQS84167.1 | AQS84165.1 | A0U92_04585 | A0U92_04575 | Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.868 |
AQS84167.1 | AQS84168.1 | A0U92_04585 | A0U92_04590 | Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
AQS84167.1 | glyA | A0U92_04585 | A0U92_04580 | Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.501 |
AQS84168.1 | AQS84165.1 | A0U92_04590 | A0U92_04575 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.876 |
AQS84168.1 | AQS84167.1 | A0U92_04590 | A0U92_04585 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
AQS84168.1 | glyA | A0U92_04590 | A0U92_04580 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.479 |
glyA | AQS84165.1 | A0U92_04580 | A0U92_04575 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.655 |
glyA | AQS84167.1 | A0U92_04580 | A0U92_04585 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.501 |
glyA | AQS84168.1 | A0U92_04580 | A0U92_04590 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
ilvD | AQS84165.1 | A0U92_00345 | A0U92_04575 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | Isopropylmalate/homocitrate/citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.499 |