STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (174 aa)    
Predicted Functional Partners:
BVU_3588
Putative GMP synthase.
  
 0.978
guaA
Glutaminne-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.976
BVU_1626
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.954
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.950
BVU_1693
Bifunctional purine biosynthesis protein, putative 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase.
  
 0.935
purH
Phosphoribosylaminoimidazole carboxy formyl formyltransferase.
  
 0.935
BVU_1602
Purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.933
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.927
BVU_1681
Putative hypoxanthine guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.922
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
  
  0.916
Your Current Organism:
Bacteroides vulgatus
NCBI taxonomy Id: 435590
Other names: B. vulgatus ATCC 8482, Bacteroides vulgatus ATCC 8482, Bacteroides vulgatus str. ATCC 8482, Bacteroides vulgatus strain ATCC 8482
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