STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (189 aa)    
Predicted Functional Partners:
guaA
Glutaminne-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
 
 0.954
BVU_3588
Putative GMP synthase.
  
 
 0.951
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.950
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.950
BVU_0876
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.935
BVU_1681
Putative hypoxanthine guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.932
BVU_0470
Nucleoside diphosphate kinase.
  
 0.928
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
  0.925
BVU_3098
Ribonucleoside-diphosphate reductase subunit A; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.921
BVU_1911
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.920
Your Current Organism:
Bacteroides vulgatus
NCBI taxonomy Id: 435590
Other names: B. vulgatus ATCC 8482, Bacteroides vulgatus ATCC 8482, Bacteroides vulgatus str. ATCC 8482, Bacteroides vulgatus strain ATCC 8482
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.