| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDI_1022 | BDI_1043 | BDI_1022 | BDI_1043 | Proline dehydrogenase, alpha subunit. | NADH:ubiquinone oxidoreductase subunit. | 0.953 |
| BDI_1022 | groL | BDI_1022 | BDI_3787 | Proline dehydrogenase, alpha subunit. | Chaperonin GroEL, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.444 |
| BDI_1022 | nnrD | BDI_1022 | BDI_1900 | Proline dehydrogenase, alpha subunit. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.742 |
| BDI_1043 | BDI_1022 | BDI_1043 | BDI_1022 | NADH:ubiquinone oxidoreductase subunit. | Proline dehydrogenase, alpha subunit. | 0.953 |
| BDI_1043 | groL | BDI_1043 | BDI_3787 | NADH:ubiquinone oxidoreductase subunit. | Chaperonin GroEL, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.412 |
| BDI_1043 | nnrD | BDI_1043 | BDI_1900 | NADH:ubiquinone oxidoreductase subunit. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.649 |
| BDI_1161 | BDI_1397 | BDI_1161 | BDI_1397 | ATP-dependent RNA helicase DeaD; Belongs to the DEAD box helicase family. | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 0.913 |
| BDI_1161 | nnrD | BDI_1161 | BDI_1900 | ATP-dependent RNA helicase DeaD; Belongs to the DEAD box helicase family. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.843 |
| BDI_1397 | BDI_1161 | BDI_1397 | BDI_1161 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | ATP-dependent RNA helicase DeaD; Belongs to the DEAD box helicase family. | 0.913 |
| BDI_1397 | nnrD | BDI_1397 | BDI_1900 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.843 |
| BDI_1896 | BDI_1899 | BDI_1896 | BDI_1899 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Hypoxanthine phosphoribosyltransferase. | 0.695 |
| BDI_1896 | adk | BDI_1896 | BDI_1898 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.765 |
| BDI_1896 | nnrD | BDI_1896 | BDI_1900 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.655 |
| BDI_1899 | BDI_1896 | BDI_1899 | BDI_1896 | Hypoxanthine phosphoribosyltransferase. | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.695 |
| BDI_1899 | adk | BDI_1899 | BDI_1898 | Hypoxanthine phosphoribosyltransferase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.971 |
| BDI_1899 | nnrD | BDI_1899 | BDI_1900 | Hypoxanthine phosphoribosyltransferase. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.646 |
| BDI_2906 | nnrD | BDI_2906 | BDI_1900 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.843 |
| BDI_3343 | nnrD | BDI_3343 | BDI_1900 | Putative ATPase/GTPase. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.724 |
| adk | BDI_1896 | BDI_1898 | BDI_1896 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.765 |
| adk | BDI_1899 | BDI_1898 | BDI_1899 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hypoxanthine phosphoribosyltransferase. | 0.971 |