Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Score
lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (281 aa)    
Predicted Functional Partners:
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.998
BDI_0689
Lipoate-protein ligase A.
 
 
 0.974
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.929
BDI_2193
Dipeptidyl aminopeptidase IV.
     
 0.813
BDI_0688
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 
 
 0.800
BDI_2191
Conserved hypothetical protein.
  
    0.669
BDI_3052
Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase.
 
  
 0.630
BDI_0690
Dihydrolipoamide dehydrogenase.
 
  
 0.629
BDI_0687
2-oxoisovalerate dehydrogenase beta subunit.
 
  
 0.612
BDI_2194
Conserved hypothetical protein.
       0.578
Your Current Organism:
Parabacteroides distasonis
NCBI taxonomy Id: 435591
Other names: P. distasonis ATCC 8503, Parabacteroides distasonis ATCC 8503, Parabacteroides distasonis str. ATCC 8503, Parabacteroides distasonis strain ATCC 8503
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