Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdhRTranscriptional regulator PdhR; Activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)    
Predicted Functional Partners:
aceE
Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.833
IDSA_00520
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.761
IDSA_00505
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.717
IDSA_00500
N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.644
IDSA_00525
E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.620
IDSA_09140
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.572
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
  
   
 0.547
IDSA_00495
Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
       0.456
IDSA_03050
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.434
IDSA_03735
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.426
Your Current Organism:
Idiomarina salinarum
NCBI taxonomy Id: 435908
Other names: CCUG 54359, I. salinarum, Idiomarina salinarum Yoon et al. 2007, KCTC 12971, Pseudidiomarina salinarum, Pseudidiomarina salinarum (Yoon et al. 2007) Jean et al. 2009, strain ISL-52
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