| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IDSA_01145 | rraA | IDSA_01145 | IDSA_09155 | GlcNAc-PI de-N-acetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.490 |
| IDSA_05055 | rraA | IDSA_05055 | IDSA_09155 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.509 |
| IDSA_08385 | rraA | IDSA_08385 | IDSA_09155 | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.500 |
| IDSA_09150 | hslU | IDSA_09150 | IDSA_09160 | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.553 |
| IDSA_09150 | hslV | IDSA_09150 | IDSA_09165 | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.553 |
| IDSA_09150 | rraA | IDSA_09150 | IDSA_09155 | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.836 |
| IDSA_10365 | rraA | IDSA_10365 | IDSA_09155 | RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.456 |
| IDSA_10835 | rraA | IDSA_10835 | IDSA_09155 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.451 |
| IDSA_11405 | rraA | IDSA_11405 | IDSA_09155 | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.562 |
| hslU | IDSA_09150 | IDSA_09160 | IDSA_09150 | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | 0.553 |
| hslU | hslV | IDSA_09160 | IDSA_09165 | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.999 |
| hslU | rraA | IDSA_09160 | IDSA_09155 | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.624 |
| hslV | IDSA_09150 | IDSA_09165 | IDSA_09150 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | 0.553 |
| hslV | hslU | IDSA_09165 | IDSA_09160 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.999 |
| hslV | rraA | IDSA_09165 | IDSA_09155 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.614 |
| mscL | rraA | IDSA_06030 | IDSA_09155 | Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.492 |
| rraA | IDSA_01145 | IDSA_09155 | IDSA_01145 | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | GlcNAc-PI de-N-acetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.490 |
| rraA | IDSA_05055 | IDSA_09155 | IDSA_05055 | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. | 0.509 |
| rraA | IDSA_08385 | IDSA_09155 | IDSA_08385 | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | 0.500 |
| rraA | IDSA_09150 | IDSA_09155 | IDSA_09150 | Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | 0.836 |