A0A166AR56 protein (Fibularhizoctonia sp. CBS109695)

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

A0A166AR56

GST N-terminal domain-containing protein. (98 aa)

Predicted Functional Partners:

A0A166RB84

0.575

A0A166UGC9

0.548

A0A166FM41

0.513

A0A166VY85

0.499

A0A166VYA0

0.499

A0A166VYP3

0.499

A0A166VYS2

0.499

A0A166GLU4

0.497

A0A166CUC3

0.491

A0A166FBI4

0.461

Your Current Organism:

Fibularhizoctonia sp. CBS109695

NCBI taxonomy Id: 436010
Other names: F. sp. CBS 109695, Fibularhizoctonia sp. CBS 109695, Fibulorhizoctonia sp. CBS 109695

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A166AR56	A0A166CUC3	GST N-terminal domain-containing protein.	Glycosyltransferase family 20 protein.	0.491
A0A166AR56	A0A166FBI4	GST N-terminal domain-containing protein.	Glycoside hydrolase family 133 protein.	0.461
A0A166AR56	A0A166FM41	GST N-terminal domain-containing protein.	Glycosyltransferase family 20 protein.	0.513
A0A166AR56	A0A166GLU4	GST N-terminal domain-containing protein.	Glyco_hydro_63 domain-containing protein.	0.497
A0A166AR56	A0A166RB84	GST N-terminal domain-containing protein.	Thioredoxin-like protein; Belongs to the GST superfamily.	0.575
A0A166AR56	A0A166UGC9	GST N-terminal domain-containing protein.	Glycosyltransferase family 20 protein.	0.548
A0A166AR56	A0A166VY85	GST N-terminal domain-containing protein.	Glutathione S-transferase C-terminal-like protein; Belongs to the GST superfamily.	0.499
A0A166AR56	A0A166VYA0	GST N-terminal domain-containing protein.	EEF1-gamma domain-containing protein.	0.499
A0A166AR56	A0A166VYP3	GST N-terminal domain-containing protein.	EEF1-gamma domain-containing protein.	0.499
A0A166AR56	A0A166VYS2	GST N-terminal domain-containing protein.	EEF1-gamma domain-containing protein.	0.499
A0A166CUC3	A0A166AR56	Glycosyltransferase family 20 protein.	GST N-terminal domain-containing protein.	0.491
A0A166CUC3	A0A166FBI4	Glycosyltransferase family 20 protein.	Glycoside hydrolase family 133 protein.	0.724
A0A166CUC3	A0A166FM41	Glycosyltransferase family 20 protein.	Glycosyltransferase family 20 protein.	0.998
A0A166CUC3	A0A166UGC9	Glycosyltransferase family 20 protein.	Glycosyltransferase family 20 protein.	0.998
A0A166FBI4	A0A166AR56	Glycoside hydrolase family 133 protein.	GST N-terminal domain-containing protein.	0.461
A0A166FBI4	A0A166CUC3	Glycoside hydrolase family 133 protein.	Glycosyltransferase family 20 protein.	0.724
A0A166FBI4	A0A166FM41	Glycoside hydrolase family 133 protein.	Glycosyltransferase family 20 protein.	0.726
A0A166FBI4	A0A166GLU4	Glycoside hydrolase family 133 protein.	Glyco_hydro_63 domain-containing protein.	0.773
A0A166FBI4	A0A166UGC9	Glycoside hydrolase family 133 protein.	Glycosyltransferase family 20 protein.	0.664
A0A166FM41	A0A166AR56	Glycosyltransferase family 20 protein.	GST N-terminal domain-containing protein.	0.513

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.786

expected number of edges:

14

PPI enrichment p-value:

0.000249

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034968

Histone lysine methylation

5 of 47

2.41

3.74

4.71e-08

GO:0051568

Histone H3-K4 methylation

4 of 20

2.68

3.6

1.82e-07

GO:0010228

Vegetative to reproductive phase transition of meristem

4 of 74

2.11

2.48

9.69e-06

GO:0080182

Histone H3-K4 trimethylation

2 of 7

2.84

1.61

0.0012

GO:0048608

Reproductive structure development

6 of 677

1.33

1.45

4.66e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042393

Histone binding

4 of 132

1.86

1.63

0.00044

GO:0003682

Chromatin binding

4 of 181

1.72

1.46

0.00076

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0048188

Set1C/COMPASS complex

3 of 14

2.71

2.46

2.97e-05

GO:0005654

Nucleoplasm

4 of 414

1.37

1.03

0.0031

GO:0140513

Nuclear protein-containing complex

5 of 869

1.14

0.88

0.0031

GO:1990234

Transferase complex

4 of 609

1.2

0.77

0.0113

GO:0005634

Nucleus

8 of 5765

0.52

0.32

0.0457

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:16168

Structural constituent of chromatin, and PKMTs methylate histone lysines

7 of 80

2.32

5.36

5.05e-12

CL:16178

Nucleosome core, and PKMTs methylate histone lysines

4 of 45

2.33

2.97

1.61e-06

CL:16291

Mixed, incl. Set1C/COMPASS complex, and Negative regulation of protein acetylation

3 of 12

2.78

2.74

8.84e-06

CL:16182

Nucleosome core, and HMGB9-like, ARID/BRIGHT DNA binding domain

3 of 23

2.5

2.34

4.10e-05

CL:16293

Set1C/COMPASS complex, and MORF/ORRM1/DAG-like

2 of 5

2.98

1.69

0.00087

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-74160

Gene expression (Transcription)

6 of 1140

1.1

0.88

0.0021

MAP-201681

TCF dependent signaling in response to WNT

2 of 29

2.22

0.83

0.0297

MAP-3214841

PKMTs methylate histone lysines

2 of 45

2.03

0.81

0.0297

MAP-3371497

HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand

2 of 66

1.86

0.73

0.0413

MAP-195721

Signaling by WNT

2 of 78

1.79

0.7

0.0444

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0048188

Set1C/COMPASS complex

4 of 15

2.81

3.82

7.98e-08

GOCC:0005654

Nucleoplasm

6 of 415

1.54

2.12

1.24e-06

GOCC:0035060

Brahma complex

2 of 3

3.2

2.07

0.00018

GOCC:0031981

Nuclear lumen

8 of 800

1.38

2.01

7.98e-08

GOCC:1902494

Catalytic complex

7 of 1276

1.12

1.2

2.46e-05

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR037353

Histone methyltransferase complex subunit ASH2

2 of 2

3.38

1.25

0.0056

IPR029295

Snf2, ATP coupling domain

2 of 3

3.2

1.25

0.0056

IPR043136

B30.2/SPRY domain superfamily

2 of 6

2.9

1.21

0.0065

IPR014012

Helicase/SANT-associated domain

2 of 6

2.9

1.21

0.0065

IPR003877

SPRY domain

2 of 5

2.98

1.21

0.0065

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01314

Snf2-ATP coupling, chromatin remodelling complex

2 of 3

3.2

1.73

0.00077

SM00449

Domain in SPla and the RYanodine Receptor.

2 of 4

3.08

1.72

0.00077

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