A0A166PDL9 protein (Fibularhizoctonia sp. CBS109695)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Score

A0A166PDL9

Uncharacterized protein. (345 aa)

Predicted Functional Partners:

A0A166ED35

Nucleotidyltransferase.

0.433

A0A166GIG3

Uncharacterized protein.

0.433

A0A166GII2

Uncharacterized protein.

0.433

Your Current Organism:

Fibularhizoctonia sp. CBS109695

NCBI taxonomy Id: 436010
Other names: F. sp. CBS 109695, Fibularhizoctonia sp. CBS 109695, Fibulorhizoctonia sp. CBS 109695

Basic Settings

Network type:

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( the edges indicate both functional and physical protein associations )

physical subnetwork

( the edges indicate that the proteins are part of a physical complex )

meaning of network edges:

evidence

( line color indicates the type of interaction evidence )

confidence

( line thickness indicates the strength of data support )

active interaction sources:

Textmining

Experiments

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Co‑expression

Neighborhood

Gene Fusion

Co‑occurrence

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Advanced Settings

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A166ED35	A0A166GII2	Nucleotidyltransferase.	Uncharacterized protein.	0.948
A0A166ED35	A0A166PDL9	Nucleotidyltransferase.	Uncharacterized protein.	0.433
A0A166GIG3	A0A166PDL9	Uncharacterized protein.	Uncharacterized protein.	0.433
A0A166GII2	A0A166ED35	Uncharacterized protein.	Nucleotidyltransferase.	0.948
A0A166GII2	A0A166PDL9	Uncharacterized protein.	Uncharacterized protein.	0.433
A0A166PDL9	A0A166ED35	Uncharacterized protein.	Nucleotidyltransferase.	0.433
A0A166PDL9	A0A166GIG3	Uncharacterized protein.	Uncharacterized protein.	0.433
A0A166PDL9	A0A166GII2	Uncharacterized protein.	Uncharacterized protein.	0.433

[ The below analysis is limited to the network nodes included in the specified statistical background ]

Network Stats

number of nodes:

number of edges:

average node degree:

5.75

avg. local clustering coefficient:

0.94

expected number of edges:

PPI enrichment p-value:

2.03e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0120009

Intermembrane lipid transfer

2 of 3

2.63

1.0

0.0228

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2105

Mixed, incl. Thiamine metabolic process, and Paraquat-inducible protein A

5 of 17

2.27

3.91

5.45e-08

CL:2124

Thiamine metabolic process

2 of 6

2.33

1.07

0.0162

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1902508

2-iminoacetate synthase complex

2 of 6

2.33

1.14

0.0127

GOCC:0005887

Integral component of plasma membrane

2 of 18

1.85

0.95

0.0213

GOCC:0016021

Integral component of membrane

3 of 67

1.46

0.92

0.0139

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04403

Paraquat-inducible protein A

2 of 2

2.8

1.31

0.0072

PF02470

MlaD protein

2 of 2

2.8

1.31

0.0072

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007498

Intermembrane transport protein PqiA-like

2 of 2

2.8

1.08

0.0174

IPR003399

Mce/MlaD

2 of 2

2.8

1.08

0.0174

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

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