STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A166TF94Histone H3; Belongs to the histone H3 family. (137 aa)    
Predicted Functional Partners:
A0A166TE46
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.984
A0A166SYT0
Clavaminate synthase-like protein.
    
 0.977
A0A166R7W4
Histone H2A; Belongs to the histone H2A family.
   
 0.970
A0A166BB13
JmjC-domain-containing protein.
    
 0.968
A0A166S1S8
WD40 repeat-like protein.
   
 0.958
A0A166W1E8
SET domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
   
 0.958
A0A166TLF2
SET domain-containing protein.
   
 0.956
A0A166KB99
WD40 repeat-like protein.
    
 0.953
A0A166TAG8
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
   
 0.952
A0A166T0H2
SET domain-containing protein.
   
 0.951
Your Current Organism:
Fibularhizoctonia sp. CBS109695
NCBI taxonomy Id: 436010
Other names: F. sp. CBS 109695, Fibularhizoctonia sp. CBS 109695, Fibulorhizoctonia sp. CBS 109695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.