A0A166XD56 protein (Fibularhizoctonia sp. CBS109695)

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

A0A166XD56

PHD-type domain-containing protein. (625 aa)

Predicted Functional Partners:

A0A166HDU2

0.867

A0A166PG40

0.867

A0A166ULY5

0.867

A0A166J6A4

0.830

A0A166V0K1

0.830

A0A166KB99

0.793

A0A166R7W4

0.785

A0A166W1E8

0.784

A0A166UL66

0.764

A0A166G683

0.744

Your Current Organism:

Fibularhizoctonia sp. CBS109695

NCBI taxonomy Id: 436010
Other names: F. sp. CBS 109695, Fibularhizoctonia sp. CBS 109695, Fibulorhizoctonia sp. CBS 109695

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A166G683	A0A166J6A4	HDAC_interact domain-containing protein.	Histone deacetylase RPD3.	0.936
A0A166G683	A0A166KB99	HDAC_interact domain-containing protein.	WD40 repeat-like protein.	0.537
A0A166G683	A0A166R7W4	HDAC_interact domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.745
A0A166G683	A0A166UL66	HDAC_interact domain-containing protein.	Uncharacterized protein.	0.558
A0A166G683	A0A166V0K1	HDAC_interact domain-containing protein.	Histone deacetylase complex catalytic component RPD3.	0.936
A0A166G683	A0A166XD56	HDAC_interact domain-containing protein.	PHD-type domain-containing protein.	0.744
A0A166HDU2	A0A166J6A4	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone deacetylase RPD3.	0.896
A0A166HDU2	A0A166KB99	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	WD40 repeat-like protein.	0.457
A0A166HDU2	A0A166R7W4	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone H2A; Belongs to the histone H2A family.	0.888
A0A166HDU2	A0A166UL66	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.782
A0A166HDU2	A0A166V0K1	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone deacetylase complex catalytic component RPD3.	0.896
A0A166HDU2	A0A166W1E8	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	SET domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.583
A0A166HDU2	A0A166XD56	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	PHD-type domain-containing protein.	0.867
A0A166J6A4	A0A166G683	Histone deacetylase RPD3.	HDAC_interact domain-containing protein.	0.936
A0A166J6A4	A0A166HDU2	Histone deacetylase RPD3.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.896
A0A166J6A4	A0A166PG40	Histone deacetylase RPD3.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.896
A0A166J6A4	A0A166R7W4	Histone deacetylase RPD3.	Histone H2A; Belongs to the histone H2A family.	0.920
A0A166J6A4	A0A166ULY5	Histone deacetylase RPD3.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.887
A0A166J6A4	A0A166W1E8	Histone deacetylase RPD3.	SET domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.699
A0A166J6A4	A0A166XD56	Histone deacetylase RPD3.	PHD-type domain-containing protein.	0.830

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.46

expected number of edges:

10

PPI enrichment p-value:

1.13e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006396

RNA processing

6 of 91

1.7

2.37

1.24e-06

GO:0034470

ncRNA processing

5 of 75

1.7

2.06

1.40e-05

GO:0008033

tRNA processing

4 of 56

1.73

1.71

0.00017

GO:0009451

RNA modification

4 of 58

1.72

1.7

0.00017

GO:0006364

rRNA processing

3 of 21

2.03

1.67

0.00050

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003723

RNA binding

5 of 134

1.45

1.36

0.00040

GO:0140098

Catalytic activity, acting on RNA

5 of 154

1.39

1.3

0.00040

GO:0008649

rRNA methyltransferase activity

2 of 6

2.4

1.18

0.0068

GO:0051539

4 iron, 4 sulfur cluster binding

3 of 43

1.72

1.13

0.0049

GO:0000049

tRNA binding

2 of 25

1.78

0.8

0.0282

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1478

0.71

0.64

5.18e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2315

Mixed, incl. tRNA processing, and NusB family

4 of 21

2.16

2.28

3.19e-05

CL:2316

Mixed, incl. NusB family, and Methylthiotransferase

3 of 12

2.28

1.73

0.00053

CL:1849

Translation, and Ribosome biogenesis

5 of 142

1.42

1.3

0.00053

CL:2073

Mixed, incl. TGS-like, and RF-1 domain

2 of 6

2.4

1.02

0.0137

CL:2110

3-5 exonuclease, and S1 domain

2 of 8

2.28

0.94

0.0183

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

5 of 399

0.98

0.59

0.0210

GOCC:0005737

Cytoplasm

7 of 1152

0.66

0.43

0.0210

GOCC:0005622

Intracellular

9 of 1930

0.55

0.37

0.0210

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0698

rRNA processing

3 of 13

2.24

2.15

7.19e-05

KW-0949

S-adenosyl-L-methionine

4 of 52

1.76

1.89

6.65e-05

KW-0963

Cytoplasm

7 of 238

1.35

1.76

1.20e-06

KW-0819

tRNA processing

3 of 28

1.91

1.65

0.00043

KW-0004

4Fe-4S

3 of 39

1.76

1.46

0.00087

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007197

Radical SAM

3 of 24

1.97

1.06

0.0094

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00729

Elongator protein 3, MiaB family, Radical SAM

3 of 18

2.1

1.78

0.00034

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