A0A167XBJ0 protein (Fibularhizoctonia sp. CBS109695)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

A0A167XBJ0

Uncharacterized protein. (209 aa)

Predicted Functional Partners:

A0A166JV37

0.654

A0A166Q581

0.654

A0A165WGS9

0.639

A0A165WH40

0.639

A0A166SQP5

0.639

A0A166TM34

0.639

A0A165Z284

0.629

A0A166H399

0.629

A0A166S2V1

0.629

A0A166GJK8

0.608

Your Current Organism:

Fibularhizoctonia sp. CBS109695

NCBI taxonomy Id: 436010
Other names: F. sp. CBS 109695, Fibularhizoctonia sp. CBS 109695, Fibulorhizoctonia sp. CBS 109695

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165WGS9	A0A166JV37	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.725
A0A165WGS9	A0A166Q581	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.725
A0A165WGS9	A0A167XBJ0	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.639
A0A165WH40	A0A166JV37	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.725
A0A165WH40	A0A166Q581	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.725
A0A165WH40	A0A167XBJ0	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.639
A0A165Z284	A0A166JV37	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.960
A0A165Z284	A0A166Q581	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.960
A0A165Z284	A0A167XBJ0	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.629
A0A166GJK8	A0A167XBJ0	Uncharacterized protein; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.608
A0A166H399	A0A166JV37	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.960
A0A166H399	A0A166Q581	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.960
A0A166H399	A0A167XBJ0	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.629
A0A166JV37	A0A165WGS9	Uncharacterized protein.	Signal peptidase complex catalytic subunit SEC11.	0.725
A0A166JV37	A0A165WH40	Uncharacterized protein.	Signal peptidase complex catalytic subunit SEC11.	0.725
A0A166JV37	A0A165Z284	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.960
A0A166JV37	A0A166H399	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.960
A0A166JV37	A0A166Q581	Uncharacterized protein.	Uncharacterized protein.	0.627
A0A166JV37	A0A166S2V1	Uncharacterized protein.	Guanine nucleotide binding protein beta subunit 2.	0.960
A0A166JV37	A0A166SQP5	Uncharacterized protein.	Signal peptidase complex catalytic subunit SEC11.	0.725

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.982

expected number of edges:

18

PPI enrichment p-value:

4.38e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046488

Phosphatidylinositol metabolic process

6 of 54

2.02

3.34

4.27e-08

GO:0046856

Phosphatidylinositol dephosphorylation

3 of 9

2.5

2.2

7.88e-05

GO:0006661

Phosphatidylinositol biosynthetic process

4 of 44

1.93

2.03

6.04e-05

GO:0046854

Phosphatidylinositol phosphate biosynthetic process

3 of 15

2.27

1.97

0.00017

GO:0006914

Autophagy

4 of 57

1.82

1.86

0.00010

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0052866

Phosphatidylinositol phosphate phosphatase activity

3 of 9

2.5

1.92

0.00027

GO:0052744

Phosphatidylinositol monophosphate phosphatase activity

2 of 3

2.8

1.19

0.0071

GO:0016772

Transferase activity, transferring phosphorus-containing groups

5 of 381

1.09

0.71

0.0125

GO:0016773

Phosphotransferase activity, alcohol group as acceptor

4 of 266

1.15

0.57

0.0449

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0035032

Phosphatidylinositol 3-kinase complex, class III

5 of 7

2.83

5.09

2.85e-10

GO:0034272

Phosphatidylinositol 3-kinase complex, class III, type II

3 of 3

2.97

2.99

3.45e-06

GO:0034271

Phosphatidylinositol 3-kinase complex, class III, type I

3 of 3

2.97

2.99

3.45e-06

GO:0000407

Phagophore assembly site

3 of 20

2.15

1.96

0.00015

GO:0005768

Endosome

5 of 124

1.58

1.9

1.56e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:13019

Mixed, incl. Inositol phosphate metabolism, and Autophagy - other

9 of 86

1.99

5.22

2.64e-14

CL:13028

Autophagy - other

5 of 22

2.33

3.77

2.91e-08

CL:13123

Inositol phosphate metabolism

4 of 23

2.21

2.77

3.11e-06

CL:13125

Inositol phosphate metabolism

3 of 17

2.22

1.92

0.00020

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00562

Inositol phosphate metabolism

6 of 37

2.18

4.45

2.37e-10

map04136

Autophagy - other

4 of 25

2.18

3.01

7.86e-07

map04070

Phosphatidylinositol signaling system

5 of 57

1.92

2.94

2.14e-07

map04138

Autophagy - yeast

5 of 108

1.64

2.21

2.27e-06

map04145

Phagosome

3 of 84

1.53

1.15

0.0026

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1660516

Synthesis of PIPs at the early endosome membrane

6 of 11

2.71

5.99

3.03e-12

MAP-1660517

Synthesis of PIPs at the late endosome membrane

5 of 8

2.77

5.16

1.81e-10

MAP-1483255

PI Metabolism

6 of 28

2.3

4.71

1.64e-10

MAP-9612973

Autophagy

6 of 59

1.98

3.64

3.97e-09

MAP-1632852

Macroautophagy

6 of 59

1.98

3.64

3.97e-09

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0035032

Phosphatidylinositol 3-kinase complex, class III

6 of 10

2.75

6.12

1.98e-12

GOCC:0034272

Phosphatidylinositol 3-kinase complex, class III, type II

4 of 4

2.97

4.32

1.11e-08

GOCC:0034271

Phosphatidylinositol 3-kinase complex, class III, type I

3 of 3

2.97

3.05

2.73e-06

GOCC:0070772

PAS complex

2 of 6

2.5

1.38

0.0029

GOCC:0016020

Membrane

7 of 1201

0.74

0.54

0.0052

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02383

SacI homology domain

2 of 4

2.67

1.02

0.0140

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR002013

SAC domain

2 of 4

2.67

0.77

0.0401

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