node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACD65666.1 | ACD66852.1 | SYO3AOP1_0015 | SYO3AOP1_1241 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_853 6-pyruvoyl tetrahydrobiopterin synthase. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_269 6-pyruvoyl tetrahydrobiopterin synthase. | 0.963 |
ACD65666.1 | queC | SYO3AOP1_0015 | SYO3AOP1_1355 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_853 6-pyruvoyl tetrahydrobiopterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.912 |
ACD65666.1 | queE | SYO3AOP1_0015 | SYO3AOP1_0569 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_853 6-pyruvoyl tetrahydrobiopterin synthase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.989 |
ACD65666.1 | queF | SYO3AOP1_0015 | SYO3AOP1_0840 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_853 6-pyruvoyl tetrahydrobiopterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.741 |
ACD66095.1 | ACD66925.1 | SYO3AOP1_0454 | SYO3AOP1_1315 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: nis:NIS_1771 anaerobic ribonucleoside triphosphate reductase. | KEGG: kcr:Kcr_0271 anaerobic ribonucleoside-triphosphate reductase. | 0.923 |
ACD66095.1 | queE | SYO3AOP1_0454 | SYO3AOP1_0569 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: nis:NIS_1771 anaerobic ribonucleoside triphosphate reductase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.803 |
ACD66209.1 | infB | SYO3AOP1_0571 | SYO3AOP1_0570 | PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: cth:Cthe_0992 ribosomal protein L7Ae/L30e/S12e/Gadd45. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.993 |
ACD66209.1 | nusA | SYO3AOP1_0571 | SYO3AOP1_0572 | PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: cth:Cthe_0992 ribosomal protein L7Ae/L30e/S12e/Gadd45. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.979 |
ACD66209.1 | queE | SYO3AOP1_0571 | SYO3AOP1_0569 | PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: cth:Cthe_0992 ribosomal protein L7Ae/L30e/S12e/Gadd45. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.778 |
ACD66209.1 | rimP | SYO3AOP1_0571 | SYO3AOP1_0573 | PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: cth:Cthe_0992 ribosomal protein L7Ae/L30e/S12e/Gadd45. | Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.941 |
ACD66852.1 | ACD65666.1 | SYO3AOP1_1241 | SYO3AOP1_0015 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_269 6-pyruvoyl tetrahydrobiopterin synthase. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_853 6-pyruvoyl tetrahydrobiopterin synthase. | 0.963 |
ACD66852.1 | queC | SYO3AOP1_1241 | SYO3AOP1_1355 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_269 6-pyruvoyl tetrahydrobiopterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.920 |
ACD66852.1 | queE | SYO3AOP1_1241 | SYO3AOP1_0569 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_269 6-pyruvoyl tetrahydrobiopterin synthase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.992 |
ACD66852.1 | queF | SYO3AOP1_1241 | SYO3AOP1_0840 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aae:aq_269 6-pyruvoyl tetrahydrobiopterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.752 |
ACD66925.1 | ACD66095.1 | SYO3AOP1_1315 | SYO3AOP1_0454 | KEGG: kcr:Kcr_0271 anaerobic ribonucleoside-triphosphate reductase. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: nis:NIS_1771 anaerobic ribonucleoside triphosphate reductase. | 0.923 |
ACD66925.1 | queE | SYO3AOP1_1315 | SYO3AOP1_0569 | KEGG: kcr:Kcr_0271 anaerobic ribonucleoside-triphosphate reductase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.803 |
infB | ACD66209.1 | SYO3AOP1_0570 | SYO3AOP1_0571 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: cth:Cthe_0992 ribosomal protein L7Ae/L30e/S12e/Gadd45. | 0.993 |
infB | nusA | SYO3AOP1_0570 | SYO3AOP1_0572 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.991 |
infB | queE | SYO3AOP1_0570 | SYO3AOP1_0569 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.798 |
infB | rimP | SYO3AOP1_0570 | SYO3AOP1_0573 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.950 |