node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACD67173.1 | dnaK | SYO3AOP1_1575 | SYO3AOP1_0889 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1296 ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.946 |
ACD67173.1 | groL | SYO3AOP1_1575 | SYO3AOP1_0586 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1296 ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.638 |
ACD67173.1 | groS | SYO3AOP1_1575 | SYO3AOP1_0587 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1296 ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.681 |
ACD67173.1 | grpE | SYO3AOP1_1575 | SYO3AOP1_0564 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1296 ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.802 |
ACD67173.1 | hslU | SYO3AOP1_1575 | SYO3AOP1_1585 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1296 ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.577 |
ACD67173.1 | hslV | SYO3AOP1_1575 | SYO3AOP1_0829 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1296 ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | 20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.428 |
ACD67206.1 | dnaK | SYO3AOP1_1608 | SYO3AOP1_0889 | PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1672 ATPase subunit of ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.946 |
ACD67206.1 | groL | SYO3AOP1_1608 | SYO3AOP1_0586 | PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1672 ATPase subunit of ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.638 |
ACD67206.1 | groS | SYO3AOP1_1608 | SYO3AOP1_0587 | PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1672 ATPase subunit of ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.681 |
ACD67206.1 | grpE | SYO3AOP1_1608 | SYO3AOP1_0564 | PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1672 ATPase subunit of ATP-dependent protease; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.802 |
ACD67206.1 | hslU | SYO3AOP1_1608 | SYO3AOP1_1585 | PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1672 ATPase subunit of ATP-dependent protease; Belongs to the ClpA/ClpB family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.577 |
ACD67206.1 | hslV | SYO3AOP1_1608 | SYO3AOP1_0829 | PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1672 ATPase subunit of ATP-dependent protease; Belongs to the ClpA/ClpB family. | 20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.428 |
ACD67361.1 | groL | SYO3AOP1_1766 | SYO3AOP1_0586 | TIGRFAM: molybdenum cofactor synthesis domain protein; molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin binding domain; molybdopterin cofactor biosynthesis MoaC region; KEGG: chu:CHU_1330 bifunctional molybdenum cofactor biosynthesis protein C/molybdopterin-binding protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.422 |
ACD67361.1 | groS | SYO3AOP1_1766 | SYO3AOP1_0587 | TIGRFAM: molybdenum cofactor synthesis domain protein; molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin binding domain; molybdopterin cofactor biosynthesis MoaC region; KEGG: chu:CHU_1330 bifunctional molybdenum cofactor biosynthesis protein C/molybdopterin-binding protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.600 |
acpP | groS | SYO3AOP1_1672 | SYO3AOP1_0587 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.682 |
acpP | rplL | SYO3AOP1_1672 | SYO3AOP1_0299 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.931 |
dnaK | ACD67173.1 | SYO3AOP1_0889 | SYO3AOP1_1575 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1296 ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | 0.946 |
dnaK | ACD67206.1 | SYO3AOP1_0889 | SYO3AOP1_1608 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: aae:aq_1672 ATPase subunit of ATP-dependent protease; Belongs to the ClpA/ClpB family. | 0.946 |
dnaK | groL | SYO3AOP1_0889 | SYO3AOP1_0586 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.981 |
dnaK | groS | SYO3AOP1_0889 | SYO3AOP1_0587 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.946 |