STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nmar_0010KEGG: mse:Msed_0640 heat shock protein HSP20. (163 aa)    
Predicted Functional Partners:
Nmar_0011
KEGG: mtp:Mthe_0531 AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; SMART: AAA ATPase.
 
  
 0.912
Nmar_0009
KEGG: ape:APE_1894 hypothetical protein.
       0.667
Nmar_0101
KEGG: afu:AF1297 cell division control protein 48, AAA family (cdc48-1); TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; SMART: AAA ATPase.
 
  
 0.655
priL
DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
     0.654
Nmar_1223
AAA family ATPase, CDC48 subfamily; KEGG: hbu:Hbut_1358 ATP-dependent protease; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
  
 0.649
dnaK
Chaperone protein DnaK; Acts as a chaperone.
  
 
 0.642
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
    0.640
Nmar_1717
Phosphate uptake regulator, PhoU; PFAM: SpoVT/AbrB domain protein; PhoU family protein; KEGG: rci:RCIX2746 phosphate uptake regulator (PhoU family).
  
     0.594
Nmar_1604
Phosphate uptake regulator, PhoU; PFAM: SpoVT/AbrB domain protein; PhoU family protein; KEGG: mba:Mbar_A1765 hypothetical protein.
  
     0.534
Nmar_0095
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.531
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.