STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvE-2Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (305 aa)    
Predicted Functional Partners:
Nmar_1070
TIGRFAM: isopropylmalate/citramalate/homocitrate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: mka:MK0391 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.987
ilvD
KEGG: sto:ST2172 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.976
Nmar_1293
PFAM: pyruvate carboxyltransferase; KEGG: mka:MK1209 2-isopropylmalate synthase.
 
 0.975
Nmar_0247
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: pfu:PF0766 putative dehydrogenase.
   
   0.945
Nmar_0245
Acetyltransferase; KEGG: hbu:Hbut_1414 predicted acetyltransferase.
  
  
 0.942
Nmar_0246
PFAM: protein of unknown function DUF343; KEGG: tpe:Tpen_0815 protein of unknown function DUF343.
       0.940
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.919
Nmar_0177
PFAM: aminotransferase class I and II; KEGG: pab:PAB1810 aspartate aminotransferase (aspB-like2).
  
 
 0.912
Nmar_0848
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: chy:CHY_2459 threonine dehydratase.
  
 
 0.909
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.905
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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