Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
PFAM- Ribosomal protein S27a; KEGG- mbn-Mboo_0241 ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family (57 aa)
Predicted Functional Partners:
annotation not available (147 aa)
PFAM- Ribosomal protein L21e; KEGG- hbu-Hbut_1660 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family (99 aa)
PFAM- Ribosomal protein L39e; KEGG- sai-Saci_1467 conserved 50S ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family (52 aa)
PFAM- Ribosomal protein L31e; KEGG- aor-AO090011000451 predicted protein Pfam- Collagen PROSITE- GLN_RICH GLU_RICH GLY_RICH LYS_RICH; Belongs to the ribosomal protein L31e family (187 aa)
KEGG- mae-Maeo_1097 ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family (115 aa)
PFAM- ribosomal protein S15; Ribosomal S13S15 domain protein; KEGG- pis-Pisl_0780 ribosomal S13S15-like protein (149 aa)
KEGG- sso-SSO5336 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family (55 aa)
PFAM- Ribosomal protein S6e; KEGG- hwa-HQ1070A ribosomal protein S6.eR; Belongs to the eukaryotic ribosomal protein eS6 family (137 aa)
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family (218 aa)