Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Nmar_1024PFAM: heat shock protein DnaJ domain protein; KEGG: cfa:609460 DnaJ (Hsp40) homolog, subfamily B, member 8. (223 aa)    
Predicted Functional Partners:
Nmar_1022
PFAM: Cupin 2 conserved barrel domain protein; KEGG: tma:TM1010 hypothetical protein.
   
 
 0.946
dnaK
Chaperone protein DnaK; Acts as a chaperone.
 
 0.943
Nmar_1021
Hypothetical protein.
       0.942
Nmar_1023
PFAM: Cupin 2 conserved barrel domain protein; KEGG: ava:Ava_C0104 cupin.
       0.942
Nmar_0095
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.872
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
   0.845
Nmar_0498
TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: rrs:RoseRS_0711 SUF system FeS assembly protein, NifU family.
  
 0.779
Nmar_1785
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_2804 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.754
Nmar_1258
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pho:PH1387 phosphoglycerate dehydrogenase.
 
 0.739
Nmar_0281
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: smr:Smar_0649 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
   
 0.714
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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