Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Nmar_1111Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: pfu:PF0024 putative glycerate kinase. (425 aa)    
Predicted Functional Partners:
Nmar_0412
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mse:Msed_0256 glyoxylate reductase.
 
 0.952
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.948
Nmar_0181
PFAM: Phosphoglycerate mutase; KEGG: sto:ST2120 hypothetical protein.
     
  0.900
Nmar_0537
Phosphoglycerate mutase; PFAM: metalloenzyme domain protein; KEGG: tpe:Tpen_1046 phosphonopyruvate decarboxylase-related protein.
     
  0.900
Nmar_0831
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating); PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: hal:VNG0095G glyceraldehyde 3-phosphate dehydrogenase.
  
  
  0.826
Nmar_0167
Transcriptional regulator, RpiR family; PFAM: sugar isomerase (SIS); KEGG: csc:Csac_1187 bifunctional phosphoglucose/phosphomannose isomerase.
    
 0.815
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.812
Nmar_0224
PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pto:PTO1166 phosphoglucomutase/phosphomannomutase; Belongs to the phosphohexose mutase family.
     
  0.800
Nmar_0413
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sai:Saci_0209 2-oxoacid-ferredoxin oxidoreductase, alfa domain.
     
  0.800
Nmar_0414
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tth:TTC1592 2-oxoacid-ferredoxin oxidoreductase.
     
  0.800
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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