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kae1 protein (Nitrosopumilus maritimus) - STRING interaction network
"kae1" - tRNA N6-adenosine threonylcarbamoyltransferase in Nitrosopumilus maritimus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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kae1tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family (327 aa)    
Predicted Functional Partners:
Nmar_1531
Mn2+-dependent serine/threonine protein kinase; PFAM- protein of unknown function RIO1; KEGG- mja-MJ1130 O-sialoglycoprotein endopeptidase (206 aa)
     
  0.988
Nmar_1534
PFAM- GTP-binding protein HSR1-related; TGS domain protein; GTPase of unknown function domain protein; KEGG- sto-ST0451 hypothetical GTP-binding protein (398 aa)
 
   
  0.948
Nmar_1429
PFAM- thiamineS protein; Ubiquitin related modifier 1 family protein (257 aa)
       
 
  0.923
fen
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (340 aa)
 
   
  0.740
Nmar_1535
Putative adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates (182 aa)
 
   
  0.727
fusA
Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (730 aa)
 
 
  0.717
rps15
PFAM- ribosomal protein S15; Ribosomal S13S15 domain protein; KEGG- pis-Pisl_0780 ribosomal S13S15-like protein (149 aa)
 
   
  0.716
Nmar_0072
PFAM- protein synthesis factor GTP-binding; Initiation factor eIF2 gamma domain protein; KEGG- afu-AF0592 translation initiation factor eIF-2 gamma subunit (420 aa)
 
        0.714
Nmar_0299
PFAM- ribulose-phosphate 3-epimerase; Transketolase domain protein; KEGG- pth-PTH_2750 transketolase, N-terminal subunit (555 aa)
 
   
  0.705
dnaG
DNA primase DnaG; SMART- Toprim sub domain protein; KEGG- sso-SSO0079 Bacterial-like DNA primase (380 aa)
   
 
  0.704
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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