node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nmar_0087 | Nmar_0672 | Nmar_0087 | Nmar_0672 | RecA/RadA recombinase-like protein; KEGG: tac:Ta1104 probable DNA repair protein Rad51 (RadA). | TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tfu:Tfu_3108 thioredoxin reductase. | 0.426 |
Nmar_0087 | Nmar_1628 | Nmar_0087 | Nmar_1628 | RecA/RadA recombinase-like protein; KEGG: tac:Ta1104 probable DNA repair protein Rad51 (RadA). | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | 0.605 |
Nmar_0095 | Nmar_0672 | Nmar_0095 | Nmar_0672 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tfu:Tfu_3108 thioredoxin reductase. | 0.516 |
Nmar_0095 | Nmar_1628 | Nmar_0095 | Nmar_1628 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | 0.658 |
Nmar_0672 | Nmar_0087 | Nmar_0672 | Nmar_0087 | TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tfu:Tfu_3108 thioredoxin reductase. | RecA/RadA recombinase-like protein; KEGG: tac:Ta1104 probable DNA repair protein Rad51 (RadA). | 0.426 |
Nmar_0672 | Nmar_0095 | Nmar_0672 | Nmar_0095 | TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tfu:Tfu_3108 thioredoxin reductase. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.516 |
Nmar_0672 | Nmar_1628 | Nmar_0672 | Nmar_1628 | TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tfu:Tfu_3108 thioredoxin reductase. | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | 0.769 |
Nmar_0850 | Nmar_1628 | Nmar_0850 | Nmar_1628 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: lpn:lpg1490 adenylate cyclase PLUS two component hybrid sensor and regulator. | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | 0.911 |
Nmar_0850 | folE | Nmar_0850 | Nmar_0038 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: lpn:lpg1490 adenylate cyclase PLUS two component hybrid sensor and regulator. | PFAM: GTP cyclohydrolase I; KEGG: hbu:Hbut_0868 GTP cyclohydrolase I. | 0.800 |
Nmar_0850 | gch3 | Nmar_0850 | Nmar_1614 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: lpn:lpg1490 adenylate cyclase PLUS two component hybrid sensor and regulator. | GTP cyclohydrolase IIa; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family. | 0.800 |
Nmar_0850 | ndk | Nmar_0850 | Nmar_0228 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: lpn:lpg1490 adenylate cyclase PLUS two component hybrid sensor and regulator. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.900 |
Nmar_1627 | Nmar_1628 | Nmar_1627 | Nmar_1628 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | 0.747 |
Nmar_1627 | ndk | Nmar_1627 | Nmar_0228 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.928 |
Nmar_1627 | queE | Nmar_1627 | Nmar_0037 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.449 |
Nmar_1628 | Nmar_0087 | Nmar_1628 | Nmar_0087 | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | RecA/RadA recombinase-like protein; KEGG: tac:Ta1104 probable DNA repair protein Rad51 (RadA). | 0.605 |
Nmar_1628 | Nmar_0095 | Nmar_1628 | Nmar_0095 | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.658 |
Nmar_1628 | Nmar_0672 | Nmar_1628 | Nmar_0672 | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tfu:Tfu_3108 thioredoxin reductase. | 0.769 |
Nmar_1628 | Nmar_0850 | Nmar_1628 | Nmar_0850 | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: lpn:lpg1490 adenylate cyclase PLUS two component hybrid sensor and regulator. | 0.911 |
Nmar_1628 | Nmar_1627 | Nmar_1628 | Nmar_1627 | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.747 |
Nmar_1628 | folE | Nmar_1628 | Nmar_0038 | SMART: regulatory protein ArsR; KEGG: mvn:Mevan_1241 anaerobic ribonucleoside-triphosphate reductase. | PFAM: GTP cyclohydrolase I; KEGG: hbu:Hbut_0868 GTP cyclohydrolase I. | 0.804 |