node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | guaA | GCA_001752345_00891 | GCA_001752345_03295 | Unannotated protein. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.978 |
argS | lysS | GCA_001752345_00891 | GCA_001752345_05216 | Unannotated protein. | Unannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.952 |
argS | purL | GCA_001752345_00891 | GCA_001752345_03236 | Unannotated protein. | Unannotated protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.700 |
argS | pyrG | GCA_001752345_00891 | GCA_001752345_01669 | Unannotated protein. | Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.886 |
argS | rplA | GCA_001752345_00891 | GCA_001752345_01107 | Unannotated protein. | Unannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.583 |
argS | rplK | GCA_001752345_00891 | GCA_001752345_01106 | Unannotated protein. | Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.624 |
argS | truB | GCA_001752345_00891 | GCA_001752345_03310 | Unannotated protein. | Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.510 |
guaA | argS | GCA_001752345_03295 | GCA_001752345_00891 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein. | 0.978 |
guaA | guaB | GCA_001752345_03295 | GCA_001752345_03298 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.998 |
guaA | guaC | GCA_001752345_03295 | GCA_001752345_04291 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.994 |
guaA | lysS | GCA_001752345_03295 | GCA_001752345_05216 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.979 |
guaA | pfp | GCA_001752345_03295 | GCA_001752345_00871 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.976 |
guaA | purL | GCA_001752345_03295 | GCA_001752345_03236 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.989 |
guaA | pyrG | GCA_001752345_03295 | GCA_001752345_01669 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.987 |
guaA | rplA | GCA_001752345_03295 | GCA_001752345_01107 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.976 |
guaA | rplK | GCA_001752345_03295 | GCA_001752345_01106 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.969 |
guaA | truB | GCA_001752345_03295 | GCA_001752345_03310 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.970 |
guaB | guaA | GCA_001752345_03298 | GCA_001752345_03295 | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.998 |
guaB | guaC | GCA_001752345_03298 | GCA_001752345_04291 | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Unannotated protein; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.924 |
guaB | purL | GCA_001752345_03298 | GCA_001752345_03236 | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Unannotated protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.782 |