STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AO062_07945Unannotated protein. (380 aa)    
Predicted Functional Partners:
RecQ
Unannotated protein.
   
 
 0.875
gyrB
Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.863
parE
Unannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.863
ligD
Unannotated protein.
 
 
 
 0.851
rnhB
Unannotated protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 
 0.849
AO062_04745
Unannotated protein.
    
 
 0.803
ku
Unannotated protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
    0.781
AO062_02905
Unannotated protein.
 
    0.588
AO062_29285
Unannotated protein.
 
    0.581
AO062_00175
Unannotated protein.
  
    0.561
Your Current Organism:
Variovorax boronicumulans
NCBI taxonomy Id: 436515
Other names: KCTC 22010, NBRC 103145, V. boronicumulans, Variovorax boronicumulans Miwa et al. 2008, strain BAM-48
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.